BMRB Entry 25112

Title:
Structural and immunological analysis of circumsporozoite protein peptides: a further step in the identification of potential components of a minimal subunit-based, chemically synthesised antimalarial vaccine.
Deposition date:
2014-07-28
Original release date:
2014-09-02
Authors:
Adriana, Bermudez; Magnolia, Vanegas; Manuel, Patarroyo
Citation:

Citation: Bermudez, Adriana; Vanegas, Magnolia; Patarroyo, Manuel. "Structural and immunological analysis of circumsporozoite protein peptides: a further step in the identification of potential components of a minimal subunit-based, chemically synthesised antimalarial vaccine."  Vaccine 26, 6908-6918 (2008).
PubMed: 18930095

Assembly members:

Assembly members:
entity, polymer, 15 residues, 1487.588 Da.

Natural source:

Natural source:   Common Name: not available   Taxonomy ID: not available   Superkingdom: not available   Kingdom: not available   Genus/species: not available not available

Experimental source:

Experimental source:   Production method: chemical synthesis

Entity Sequences (FASTA):

Entity Sequences (FASTA):
entity: KNSFSLGENPNANPX

Data sets:
Data typeCount
1H chemical shifts87

Additional metadata:

  • Assembly
  • Samples and Experiments
  • Software
  • Spectrometers
  • Hide all

Assembly:

Entity Assembly IDEntity NameEntity ID
1entity1

Entities:

Entity 1, entity 15 residues - 1487.588 Da.

1   LYSASNSERPHESERLEUGLYGLUASNPRO
2   ASNALAASNPRONH2

Samples:

sample_1: entity 8 mM; trifluoroethanol 30 v/v; water 70 v/v

sample_conditions_1: temperature: 295 K; pH: 3.7; pressure: 1 atm

Experiments:

NameSampleSample stateSample conditions
2D DQF-COSYsample_1isotropicsample_conditions_1
2D 1H-1H TOCSYsample_1isotropicsample_conditions_1
2D 1H-1H NOESYsample_1isotropicsample_conditions_1

Software:

InsightII, Accelrys Software Inc. - geometry optimization, refinement

NMR spectrometers:

  • Bruker DRX 600 MHz